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GA Review

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This review is transcluded from Talk:Thymus/GA1. The edit link for this section can be used to add comments to the review.

Reviewer: Cinadon36 (talk · contribs) 13:31, 17 April 2020 (UTC)[reply]


Hi all, I will have a look at this article. Cinadon36 13:31, 17 April 2020 (UTC)[reply]

Thanks for taking up this review. I look forward to your assessment. --Tom (LT) (talk) 23:23, 17 April 2020 (UTC)[reply]

Good job Tom (LT). I 've just read it one time and it really looks fine. Before I go into a detailed review, I got a question for you. Since the article is on human Thymus, I didn't understand why are there sections on "Other animals" and "Society and culture". The latter section is a bit awkward since it consists of only one sentence. Cinadon36 12:20, 18 April 2020 (UTC)[reply]

  • Thanks for your initial review Cinadon36, I look forward also to your detailed review. Sections are titled according to the relevant manual of style entry (WP:MEDMOS#Anatomy). If it is OK with you, I prefer to leave 'society and culture' as, although it's a small section, it may be expanded by other editors in the future, although I'm not aware of any specific things that should be included. Other animals is a standard heading in most anatomical articles. It is termed 'other' in relation to humans (also an animal). --Tom (LT) (talk) 00:46, 19 April 2020 (UTC)[reply]

On Verifiability

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Neutrality, well written, Stability, media

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Easily pass all these criteria. I would have used the additional images within the main body of the article, at section Development. But then, there would be too many images there. Cinadon36 08:00, 20 April 2020 (UTC)[reply]

On prose

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Ok, here are some of my comments on prose. Sorry for moving on too slowly on this GAN. Cinadon36 08:55, 23 April 2020 (UTC)[reply]

  • At Structure, there is a section for microanatomy, but no mention of macroanatomy. I feel it should be mentioned somewhere where the thymus is sited. There is a sentence at the lede, but it is not the best place possible, it should be somewhere at the main body of the article.Cinadon36 08:55, 23 April 2020 (UTC)[reply]
    • Currently the article says: "and stretch from below the thyroid in the neck to as low as the cartilage of the fourth rib.[1] The lobes are covered by a capsule.[3] The thymus lies beneath the sternum, rests on the pericardium, and is separated from the aortic arch and great vessels by a layer of fascia" in the structure section, which is a description of the location of the thymus. I worry that this isn't clear to lay readers but am having trouble thinking of a better way to describe it at the moment. Do you have any suggestions? --Tom (LT) (talk) 00:00, 25 April 2020 (UTC)[reply]
      • What about "Thymus is sited/located in the centre of the chest/thorax, it lies just behind the sternum in a space called anterior mediastinum" Or something similar? In any case, I trust your better judgement on this, do not feel obliged to follow my suggestions. Cinadon36 08:34, 25 April 2020 (UTC)[reply]
  • Some of this is because of hormones and cytokines secreted by the thymus, including thymulin, thymopoietin, and thymosins. Is it possible to clarify which part(cortex, medulla)/cells are producing these molecules? Cinadon36 09:03, 23 April 2020 (UTC)[reply]
    •  Partly done have clarified the sentence, but as the cells are present in different concentrations within the medulla and cortex, and therefore these hormones are going to be present in various concentrations throughout, I don't think I'm going to find a very useful answer here . --Tom (LT) (talk) 02:52, 7 May 2020 (UTC)[reply]
  • lede:Cells in the thymus can be divided into thymic stromal cells and cells of hematopoietic origin (derived from bone marrow resident hematopoietic stem cells). I cant find a discussion of this sentence in the main body of the article.Cinadon36 13:22, 25 April 2020 (UTC)[reply]
  • Clinical significance is not covered at the lede. Cinadon36 13:38, 25 April 2020 (UTC)[reply]
    •  Done
  • Virtual Slidebox at Univ. Iowa Slide 287 site content not accessible to the reader.[2]Cinadon36 14:17, 25 April 2020 (UTC)[reply]

Great, passing, thanks Tom (LT) for such a beautiful article. It is not far from FA but that's another story. Wishing you all the best, Cinadon36 12:59, 7 May 2020 (UTC)[reply]

This section is grossly false: "Removal of the thymus in infancy results in often fatal immunodeficiency, because functional T cells have not developed.[2] In older children and adults, which have a functioning lymphatic system with mature T cells also situated in other lymphoid organs, the effect is lesser, and limited to failure to mount immune responses against new antigens."

This is dangerously incorrect since pretty much any major infant heart surgery involves removal of the thymus. These patients go on to live decades. There is no evidence whatsoever that these patients suffer "fatal immunodeficiency".

Source: https://journals.sagepub.com/doi/abs/10.1177/2150135111403328 — Preceding unsigned comment added by 107.129.183.124 (talk) 03:29, 7 October 2020 (UTC)[reply]

Anatomical Right & Left

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The diagram is pointing to the observer's left and right; not the subjects. 2A00:23C8:1D85:B000:35C4:3495:125B:3C39 (talk) 20:16, 24 October 2024 (UTC)[reply]