Talk:Folinic acid

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Ideal sources for Wikipedia's health content are defined in the guideline Wikipedia:Identifying reliable sources (medicine) and are typically review articles. Here are links to possibly useful sources of information about Folinic acid.

PubMed provides review articles from the past five years (limit to free review articles)
The TRIP database provides clinical publications about evidence-based medicine.
Other potential sources include: Centre for Reviews and Dissemination and CDC

Heading

In accordance with Wikipedia:WikiProject_Drugs naming policy, I propose we move this page to the INN calcium folinate. If you have any concern with this proposal, please discuss it on this page. Matt 23:03, 21 Dec 2004 (UTC)

No probs, I completely agree with the move. It was my mistake for not writing the original article under calcium folinate anyway... -Techelf 05:03, 23 Dec 2004 (UTC)

Hi. I was wondering how folinic acid is commonly derived. Is it synthetic?

Citrovorum Factor

I don't understand why the article has a section on Citrovorum Factor WTF??

Jerome Samson (talk) 15:20, 9 February 2011 (UTC)[reply]

Synonyms

Hi. The Synonym section is incorrect. Folinic acid isn't the same as 5-MTHF, L-methylfolate, Metafolin, Quatrefolic, etc. Take a look at the chemical structures and where they fit in the folate/methylation cycles. JDJ88 (talk) 19:37, 6 July 2015 (UTC)[reply]

Although it is the same as calcium folinate, which I buy OTC. I suspect the "Rx only" label for this vitamin applies only to high dosages, since all high dosage forms of folic acid are prescription only, whatever form is used. 173.228.54.27 (talk) 18:20, 27 September 2015 (UTC)[reply]

Reference [10] should be removed.

The reference [10], "How a vitamin cured my anxiety: Elisa Black’s story of lifelong struggle and new hope for the future" is garbage—it should be removed. — Preceding unsigned comment added by 67.5.227.138 (talk) 21:18, 1 October 2016 (UTC)[reply]

Not in article as of Jan 2019. David notMD (talk) 21:10, 9 January 2019 (UTC)[reply]

I've added the mention of Cerebral folate deficiency

I've added the mention of Cerebral folate deficiency because I'd like that article to have more incoming links, and because folinic acid treatment is quite specific to this syndrome, as opposed to the more "generic" Folate deficiency, which can also be treated with folic acid. --CopperKettle 16:58, 15 January 2019 (UTC)[reply]

Autism

"Autism can feature cerebral folate deficiency. Cerebral folate receptor autoantibodies can be present in autism spectrum disorder.^[1] There are some empirical indications that folinic acid might improve verbal communication in children with non-syndromic autism spectrum disorder (ASD).^[2] Folinic acid and methylcobalamin treatment on glutathione redox status in children with autism.^[3]"

Is all based on primary sources. We need some decent secondary sources before making these claims. Doc James (talk · contribs · email) 07:55, 11 January 2020 (UTC)[reply]

References

I removed the reference to statement on interaction with fluorouracil

Hi! I've removed the ref (PMID 7627739) to the statement on interaction with fluorouracil. I downloaded the paper, and it only says that the two drugs, when mixed in one container, may cause precipitation in the liquid. There's no mention of pharmacological interaction in the patient's body. Yours, --CopperKettle (talk) 09:57, 22 January 2023 (UTC)[reply]

[1] ttps://www.nature.com/articles/mp2011175

[2] ttps://www.nature.com/articles/mp2016168

[3] ttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC2647708/

[1]

[2]

[3]